Original sin is the doctrine which holds that human nature has been morally and ethically corrupted due to the disobedience of mankind's first parents to the revealed will of God. In the Bible, the first human transgression of God's command is described as the sin of Adam and Eve in the Garden of Eden resulting in what theology calls the Fall of mankind. The doctrine of original sin holds that every person born into the world is tainted by the Fall such that all of humanity is ethically debilitated, and people are powerless to rehabilitate themselves, unless rescued by God.
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There are wide-ranging disagreements among Christian groups as to the exact understanding of this doctrine. For example, it has been common in Western Christianity to impute inherited guilt for the Original Sin alongside the debilitated condition, while such doctrine is repugnant to the Eastern Orthodox. Some so-called Christian groups deny Original Sin, altogether.
G. K. Chesterton once said that original sin is the one Christian doctrine that is empirically verifiable and validated by 3500 years of human history.